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The research areas pharmacogenomics and individualised pharmacotherapy are concerned with the variability of patients' drug responses that is caused by inborn genetic differences. Research in this area concentrates on expanding the knowledge of molecular, preclinical, and clinical principles in order to arrive at a personalised pharmacotherapy. The aim is to identify the exact causes for individual differences and the variability of desired drug reactions as well as of adverse reactions and interactions of medicinal products. The findings allow the development of modern and personalised treatments and lead to improvements in the patient safety of new medicinal products and therapeutic concepts.