Direct Healthcare Professional Communication (DHPC) on Livopan (Nitrous Oxide/Oxygen) 50 %/50 % gas for medical use, compressed: Risk of gas leakage and interruption of gas supply to patients when the flow rate is above 8 l/min
2025.04.22
Active substance: Nitrous Oxide, Oxygen
The company Linde Sverige AB informs about a quality defect of the medicinal product Livopan (gas for medical use, compressed) when used with a Fir Tree connector for direct connection with O2/N2O breathing systems. The gas nitrous oxide contained in Livopan can act as a coolant and cause the valve and lines to freeze at flow rates above 8 l/min. This can result in gas leaks, blockage of the gas supply, interruption of oxygen supply, and hypoxia. The company points out that the flow rate should always be set below 8 l/min.
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